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  [摘要] 目的 观察心脏瓣膜病合并肺动脉高压行瓣膜手术的疗效，分析影响其手术疗效的因素。 方法 采用手术前后肺动脉收缩压(PASP)、左心室射血分数(LVEF)、术后并发症发生率及死亡率等作为疗效观察指标，评价不同年龄、性别、心功能分级及术前PASP等级患者的疗效。 结果 年龄> 60岁组患者的术后PASP变化值[(25.86±4.27)mm Hg]及LVEF变化值[(2.64±1.62)%]均低于年龄≤ 60岁组患者[(28.37±3.53)mm Hg，(3.71±1.95)%]，而术后并发症发生率(23.33%)及死亡率(13.33%)均高于年龄≤ 60岁组(12.50%，5.00%)，差异均有统计学意义(P 0.05)。随着心功能等级的升高，术后PASP值逐渐升高，LVEF值逐渐降低，并且并发症及死亡率也逐渐升高，差异均有统计学意义(P 60 years old patients were lower than those of ≤ 60 years old patients [(28.37±3.53) mm Hg, (3.71±1.95)%], while the incidence of complications (23.33%) and mortality (13.33%) of > 60 years old patients were higher than those of ≤ 60 years old group (12.50%,5.00%), the differences were statistically significant (P 0 ......