[摘要] 目的 探析吡柔比星膀胱灌注联合化疗治疗晚期膀胱癌的临床效果。方法 整群==选取2013年4月—2015年2月来该院就诊的75例晚期膀胱癌患者，随机分为对照组37例和观察组38例。对照组患者单纯采用化疗；观察组患者则在此基础上加用吡柔比星膀胱灌注治之，连续治疗2个月。评价治疗前后患者的生活质量，计算有效率，观察治疗过程中的不良反应。结果 观察组患者的生活质量改善明显优于对照组患者，其与生活质量相关的角色、认知、感情、社会功能得分明显高于对照组(P0.05)。结论 吡柔比星膀胱灌注联合化疗治疗晚期膀胱癌疗效确切，利于提高患者的生活质量，副作用少，值得临床广泛推广。

 [关键词] 吡柔比星；膀胱灌注；化疗；膀胱癌

 [中图分类号] R737.14 [文献标识码] A [文章编号] 1674-0742(2015)09(b)-0053-03

 [Abstract] Objective To investigate the clinical efficacy of treating the advanced bladder cancer with pirarubicin for bladder perfusion combined chemotherapy. Methods 75 patients with advanced bladder cancer admitted to our hospital from April 2013 to February 2015were randomly divided into control group of 37 cases and observation group of 38 cases. The patients in the control group were treated with chemotherapy； while those in the observation group were treated with pirarubicin for bladder perfusion combined chemotherapy for 2 months continuously. We evaluated the patient's quality of life ...... 第 1 2 页 下一页
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