[摘要] 目的 探討甲硝唑缓释药膜联合盐酸米诺环素治疗牙周炎的疗效及安全性。方法 方便选取2018年2月—2019年2月该院接收的102例牙周炎患者，为该次观察对象并予以随机对照，即常规组51例用甲硝唑缓释药膜，研究组51例则在常规组基础上加用盐酸米诺环素。结果 研究组临床治疗总体疗效96.08%高于常规组84.31%(χ2=8.011，P0.05)，但研究组复发率3.92%低于常规组17.65%(χ2=9.748，P, http://www.100md.com
 [关键词] 甲硝唑缓释药膜;盐酸米诺环素;牙周炎;治疗效果;不良反应

 [中图分类号] R781.4+2 [文献标识码] A [文章编号] 1674-0742(2019)11(a)-0009-03

 Efficacy and Safety of Metronidazole Sustained-release Membrane Combined with Minocycline Hydrochloride in the Treatment of Periodontitis

 XIONG Bao-ping

 Department of Stomatology， Qufu Hospital of Traditional Chinese Medicine， Qufu， Shandong Province， 273100 China
, 百拇医药
 [Abstract] Objective To investigate the efficacy and safety of metronidazole sustained-release membrane combined with minocycline hydrochloride in the treatment of periodontitis. Methods From February 2018 to February 2019， 102 patients with periodontitis were Convenient eleetion enrolled in this hospital. The subjects were randomized to control， ie， 51 patients in the routine group were treated with metronidazole sustained-release drug film. Study group with 51 cases， minocycline hydrochloride was added to the conventional group. Results The overall efficacy of clinical treatment in the study group was 96.08% higher than that in the conventional group (84.31%， χ2=8.011， P0.05)， the recurrence rate of the study group was 3.92% lower than that of the conventional group (17.65%) (χ2=9.748， P, http://www.100md.com(熊宝平) 第 1 2 3 页 下一页
 百拇医药网 http://www.100md.com/html/paper/1674-0742/2019/31/04.htm