【摘要】 目的:探讨来氟米特治疗风湿免疫性疾病的效果。方法:选取2015年2月-2016年2月笔者所在医院收治的100例风湿免疫性疾病患者为研究对象,按照随机数字表法分为两组,每组50例。对照组采用单一激素治疗,来氟米特组采用激素联合来氟米特治疗。比较两组患者的病情缓解率;关节压痛消失时间、关节肿胀消失时间、晨僵持续时间、正常活动时间;干预前后患者血清尿酸、超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)、血沉水平及晨僵时间;干预前后患者生存质量;脱发、肝肾损害、胃肠道损害等药物不良反应发生率。结果:来氟米特组患者病情缓解率高于对照组,差异有统计学意义(字2=6.016,P0.05);干预后来氟米特组血清尿酸、hs-CRP、血沉水平及晨僵时间均短于对照组,差异均有统计学意义(P0.05);干预后来氟米特组生存质量评分显著高于对照组,差异有统计学意义(t=9.813,P0.05),and the serum uric acid,hs-CRP,erythrocyte sedimentation level and morning stiff time in Leflunomide group were shorter than those in the control group,and the differences were statistically significant(P0.05).After intervention,the score of quality of life in Leflunomide group was significantly higher than that in the control group,the difference was statistically significant(t=9.813,P, 百拇医药(陈丽珍) 第 1 2 3 页 下一页
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