【摘要】脂蛋白肾病是一种罕见的肾脏疾病，主要病理特点为明显扩张的肾小球毛细血管襻，腔内脂蛋白栓子形成，免疫荧光或免疫组织化学染色提示载脂蛋白B(ApoB)或ApoE阳性，伴有明显的血清ApoE浓度升高。罕见的ApoE基因变异可能导致脂蛋白肾病。该文介绍了脂蛋白肾病的流行病学、发病机制、临床特点、病理特点和治疗相关的研究进展。

 【关键词】脂蛋白肾病；载脂蛋白E；基因突变

 【Abstract】Lipoprotein glomerulopathy is a rare renal disease， mainly pathologically characterized by enlarged glomerular capillaries and intraglomerular lipoprotein thrombosis Immunofluorescent or immunohistochemical staining yields positive results of apolipoprotein B (ApoB) or ApoE， accompanied by significant elevation of serum ApoE concentration ApoE gene mutation is probably the cause of lipoprotein glomerulopathy In this article ...... 第 1 2 3 页 下一页
 百拇医药网 http://www.100md.com/html/paper/0253-9802/2017/12/01.htm
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