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 参见附件。

  [摘要] 目的 观察131I治疗青少年甲状腺功能亢进症(甲亢)的疗效，探讨其治疗的可行性。 方法 对我院收集的120例青少年甲状腺功能亢进症患者进行131I治疗，治疗1年内定期复查肝功能、甲状腺功能、摄131I率及甲状腺显像(可计算甲状腺重量)，综合评价其治疗效果。 结果 120例患者治疗前后肝功能指标变化比较，差异无统计学意义(P > 0.05)；治疗前后甲状腺功能指标、24 h摄131I率、甲状腺重量比较，差异均有统计学意义(P 0.05)。 结论 131I治疗青少年甲状腺功能亢进症疗效安全有效，但治疗时仍需慎重，以防甲低的发生。

 [关键词] 青少年甲状腺功能亢进症；131I；甲状腺功能减退症

 [中图分类号] R581.1 [文献标识码] A [文章编号] 1673-7210(2012)02(b)-0056-02

 Clinical observation of 131I in the treatment of adolescent patients with hyperthyroidism

 GUAN Zexiong GUAN Hanfen HUANG Zhujiao PENG Guirong

 Department of Nuclear Medicine, the People's Hospital of Yangjiang City, Guangdong Province, Yangjiang 529500, China

 [Abstract] Objective To observe the effect of 131I in the treatment of adolescent patients with hyperthyroidism, and explore the feasibility of treatment. Methods 120 cases of adolescent patients with hyperthyroidism were treated with 131I. Liver function, thyroid function, the rate of taking 131I at 24 h and thyroid image (counted the thyroid weight) were checked in a year. Results Among 120 cases of patients with hyperthyroidism, the liver function had no significant difference between before and after treatment (P > 0.05); the index of thyroid function, the rate of taking 131I at 24 h and thyroid weight were significant differences between before and after treatment (P 0.05). Conclusion 131I treatment is safe and effective in the treatment of adolescent patients with hyperthyroidism, but the treatment need take care, in order to aviode the occurrence of hypothyroidism.

 [Key words] Adolescent hyperthyroidism; 131I; Hypothyroidism

 甲状腺功能亢进症(甲亢)是内分泌系统常见的一种疾病 ......