摘要 目的：探討扶正消瘤汤辅助化疗对乳腺癌患者术后肿瘤标志物水平及免疫功能的影响。方法：选取乳腺癌患者74例，根据电脑产生的随机数字分为观察组和对照组，各37例，2组患者均给予常规化疗方案，观察组在此基础上增加扶正消瘤汤治疗。比较2组患者治疗后血清肿瘤标志物水平，治疗前后免疫功能及乳腺癌生命质量测评量表(FACT-B)评分。结果：治疗后观察组血清CEA、CA125、CA153、TSGF、VEGF-A、IGF-1及TK1水平均明显低于对照组( P 0.05)；治疗后观察组FACT-B评分明显升高，且明显高于对照组，差异有统计学意义( P , http://www.100md.com
 关键词 乳腺癌；化疗；扶正消瘤汤；肿瘤标志物；免疫功能；生命质量

 Adjuvant Effect of Fuzheng Xiaoliu Decoction for Chemotherapy on Tumor Markers and immunity of Postoperative Breast Cancer Patients

 Zhou Shifan

 (Oncology Department， The Second Affiliated Hospital of Henan University of TCM， Zhengzhou 450002， China)

 Abstract Objective： To explore adjuvant effect of Fuzheng Xiaoliu Decoction for chemotherapy on tumor markers and immunity of postoperative breast cancer patients. Methods： A total of 74 breast cancer patients were selected and divided into treatment group and control group according to the random numbers generated by computer， with 37 cases in each group. The two groups were treated with conventional chemotherapy， while treatment group additionally treated with Fuzheng Xiaoliu Decoction. Levels of tumor markers， immunity and the scores of Functional Assessment of Cancer Therapy-Breast Quality of Life Instrument (FACT-B) in the two groups before and after the treatment were compared. Results： The levels of serum CEA， CA125， CA153， TSGF， VEGF-A， IGF-1 and TK1 in the treatment group after the treatment decreased significantly compared with those before the treatment ( P 0.05). The FACT-B scores in the treatment group after the treatment increased significantly and were higher than those in the control group ( P , 百拇医药(周世繁) 第 1 2 3 页 下一页
 百拇医药网 http://www.100md.com/html/paper/1673-7202/2017/07/15.htm