第1页参见附件(1920KB,2页)。
[摘要] 目的 探讨急性颈脊髓损伤并发低钠血症的发病机制和治疗方法。方法 回顾性分析2006年2月至2010年3月收治的17例颈髓损伤患者的临床资料。结果 轻中度患者血钠和尿量很快恢复正常;5例重度患者血钠和尿量恢复正常,最短恢复时间18d,最长时间39d。2例好转,血钠和尿量到出院时仍未达正常水平。 结论低钠血症是急性颈髓损伤后常见的并发症,颈髓损伤程度越重,低钠血症发生率越高。其发生机制可能与颈髓损伤后交感神经系统受抑制,血管紧张素Ⅱ、醛固酮分泌减少有关。大量补钠、补液可纠正低钠血症,补充适当的胶体液有利于加快血钠水平的恢复。
关键词:脊髓损伤低钠血症高渗盐
Clinical analysis on Hyponatremia after acute cervical spinal cord injury
Guo Wei-zhuang
(Shenzhen Second People's Hospital Spine Surgery518000,China)
AbstractObjectiveTo investigate the mechanism and the treatment of hyponatremia after acute cervicalspinal cord injury. MethodsRetrospective analysis from February 2006 to March 2010 17 cases of cervical spinal cord injury admitted to the clinical data. ResultsSerum sodium and urine output in patients with mild to moderate back to normal soon; five cases of severe hyponatremia and urine of patients back to normal, the shortest recovery time of 18 days, the longest 39 days. 2 patients improved to the sodium level and urine output has not reached normal levels at discharge. Conclusion Acute hyponatremia is a common complication after spinal cord injury, spinal cord injury more severe, higher incidence of hyponatremia. Its mechanism may be related to spinal cord injury by inhibition of the sympathetic nervous system, angiotensin Ⅱ, the reduced aldosterone secretion. Fill a large number of sodium, fluid rectified hyponatremia, add the appropriate colloid help speed up the recovery of serum sodium levels.
KeywordsSpinal Cord Injury,Hyponatremia,Hypertonic saline
中图分类号:R322.81 文献标识码:B 文章编号:1004-7484(2011)05-0031-02
低钠血症是急性颈髓损伤(CSCI)患者早期最常见的并发症,其发生率在51.35%~92.90%。临床处理不当,容易造成颈脊髓损伤加重,甚至危及病人生命。本文对2006年2月至2010年3月我科收治的17例颈脊髓损伤并发尿崩症、低钠血症患者的临床资料进行回顾分析,探讨其机理、诊断和治疗。
1 资料与方法
1.1一般资料
本组均系外伤后不同程度急性颈脊髓损伤。共17例,男14例,女3例;年龄22~52岁,平均36 5岁。致伤原因:车祸伤8例,坠落伤4例,重物砸伤2例,跌伤2例,击伤1例。脊髓损伤Frankel分级:A级6例,B级4例,C级3例,D级4例。
1.2临床表现和实验室检查
出现低钠血症17例,从脊髓损伤到出现时间3~11d,平均6 8d。脊髓损伤情况A级6例,B级4例,C级3例,D级4例。伴其它部位轻微伤8例:颅脑伤3例,不需特殊处理;胸部和四肢伤5例,相应简单处理。低钠血症程度:①轻中度12例:轻度6例,血钠130 ~134mmol/L;中度6例,血钠125 ~129mmol/L。轻中度高峰时尿量:(3400±380)ml/24h。②重度5例,血钠130mmol/L的6例患者,均常规补液,未特殊处理,1周内血钠均恢复正常;血钠
http://www.100md.com/html/paper/1004-7484/2011/05/19.htm
您现在查看是摘要介绍页,详见PDF附件(1920KB,2页)。
