【摘要】 目的：探讨全血糖化血红蛋白(HbA1c)及血清胱抑素C(Cys-C)、同型半胱氨酸(Hcy)水平与糖尿病患者肾脏功能损害的相关性。方法：选取2014年7月-2015年8月本院收治的2型糖尿病患者181例作为观察组，根据尿蛋白排泄率(UAER)分为三组，分别为正常蛋白尿组(UAER300 mg/24 h，n=58)，另选取同期在本院体检的健康志愿者60例作为对照组。所有患者及健康体检者均测量全血HbA1c、Cys-C、Hcy水平，估算肾小球滤过率(eGFR)，并进行组间比较，采用Pearson相关分析探讨全血HbA1c及血清Cys-C、Hcy水平与eGFR的关系。结果：HbA1c、Cys-C、Hcy水平在对照组、正常蛋白尿组、微量蛋白尿组、临床蛋白尿组中依次升高，而eGFR依次降低，组间差异均有统计学意义(P300 mg/24 h，n=58) respectively， and 60 cases of healthy volunteers at the same period were selected as control group.The levels of whole blood HbA1c and Cys-C，Hcy were detected，and the rate of glomerular filtration (eGFR) were estimated.The relationship of HbA1c，Cys-C，Hcy levels and eGFR were analyzed by Pearson correlation analysis.Result：There were statistically significant difference between the four groups on the levels of HbA1c，Cys-C，Hcy，eGFR (P, 百拇医药(林彩凤) 第 1 2 3 页 下一页
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