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  [摘要] 目的 探讨超声造影在肝硬化基础上低度和高度不典型增生结节的表现。 方法 对本院2009年6月～2011年6月经病理确诊的17个低度和20个高度不典型增生结节患者的二维超声和超声造影检查资料进行回顾性分析，观测指标为病灶的大小、回声、边界、声晕及血供。 结果 超声造影显示低度不典型增生结节(LGDN)和高度不典型增生结节(HGDN)在动脉期、门脉期、延迟期表现无明显差异，差异无统计学意义(P > 0.05)。 结论 超声造影在肝硬化基础上低度和高度不典型增生结节的表现相似；对LGDN与HGDN只有通过穿刺病理检查确诊，但通过超声造影的三期表现及各期增强水平表现，可以反映出肝脏不同的血供变化，对肝细胞癌的早期诊断提供帮助。

 [关键词] 超声造影；肝硬化；低度不典型增生结节；高度不典型增生结节

 [中图分类号] R445.1 [文献标识码] A [文章编号] 1674-4721(2012)02(a)-0093-02

 Enhanced contrast ultrasound imaging results of low-grade dysplastic nodules and high-grade dysplastic nodules in liver cirrhosis

 LI Jiancong1 ZHOU Lihuan2

 Ultrasonography Department, Central Hospital of Kaiping City in Guangdong Province, Kaiping 529300, China

 [Abstract] Objective To investigate the features of enhanced contrast ultrasound imaging results of low-grade dysplastic nodules (LGDN) and high-grade dysplastic nodules(HGDN) in liver cirrhosis. Methods Two-dimensional ultrasound and ultrasonic imaging data of 17 low-grade dysplastic nodules patients and 20 high-grade dysplastic nodules patients were analyzed retrospectively. The patients were pathologically confirmed in the author's hospital from June 2009 to June 2011, and the lesion size, reverberation, boundary, sound dizzy and blood supply were observed. Results Ultrasound imaging showed no significant differences between low-grade dysplastic nodules and high-grade dysplastic nodules at arterial phase, portal phase and delayed phase (P > 0.05). Conclusion Ultrasound imaging of low-grade dysplastic nodules and high-grade dysplastic nodules in cirrhosis are of similar features; low-grade dysplastic nodules and high-grade dysplastic nodules can be diagnosed only by biopsy, but the three-phase enhanced performance ultrasound imaging can show the different blood supply changes in the liver, thus is helpful for the early diagnosis of hepatocellular carcinoma.

 [Key words] Ultrasound imaging; Cirrhosis; Low-grade dysplastic; High-grade dysplastic nodules

 近年来，我国肝病的发病人数逐年上升。肝硬化基础上低度和高度不典型增生结节是指直径超过1 mm的因肝细胞增生而形成的肝内结节[1] ......