摘要本研究基于中医“四时五藏阴阳”理论，从代表季节变化的光照因素切入，系统性地观察了冬夏季节变化对下丘脑垂体性腺轴生理功能的影响及褪黑素在此过程中的调节作用，以探讨该理论所具有的科学内涵。实验检测了雄性金黄地鼠血浆、下丘脑、垂体、睾丸组织中MT、GnRH、LH、FSH、T的含量，以及各组织中MR的含量，结果发现，下丘脑GnRH、垂体LH、FSH、睾丸T的含量均表现为夏高冬低(P005)，血浆LH则在冬至更高(P, 百拇医药
 Study on Effects of Seasonal Changes of Winter and Summer on the Function of Male

 Golden Hamster′s Hypothalamicpituitarygonad Axis

 Yang Zongchun1， Han Junge2， Zhang Na1， Liu Xu1， Liu Xiaoyan1，Guo Xiazhen1

 (1 Beijing University of Chinese Medicine， Beijing 100029， China； 2 Beijing Fangshan

 Traditional Chinese Medicine Hospital， Beijing 102488， China)
, 百拇医药
 AbstractBased on the “yinyang of the four seasons and the five viscera” theory of TCM， this study systematically observed the effects of seasonal change of winter and summer on the hypothalamuspituitary gonad axis function and the role of melatonin in this seasonal change， from the representative factors into the seasonal variation of illumination， to explore the scientific connotation of this theory. The content of MT， GnRH， LH， FSH， T in the plasma， hypothalamus， pituitary and testicular tissues of male golden hamster rats were detected， and the content of MR in various tissues were detected. The results showed that the content of GnRH in hypothalamus， LH and FSH in pituitary， T in testicular were characterized by high in summer and low in winter (P005). Content of LH in plasma was higher in winter (P, http://www.100md.com(杨宗纯 韩俊阁 张娜 刘絮 刘晓燕 郭霞珍) 第 1 2 3 4 5 页 下一页

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 百拇医药网 http://www.100md.com/html/paper/1673-7202/2018/05/05.htm