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NCBI provides a variety of resources that allow developers to access and manipulate NCBI data in their applications.

APIs

Programming interfaces including the E-utilities, BLAST URL API and PUG

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Software libraries including the C++ and SRA toolkits

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Schema, DTDs and other data specifications

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USING E-UTILITIES

An introduction to NCBI's Entrez programming utilities, the API to the Entrez system of databases at NCBI.